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Lysine 6-dehydrogenase
・ Lysine carbamoyltransferase
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Lysine 6-dehydrogenase : ウィキペディア英語版
Lysine 6-dehydrogenase

Lysine 6-dehydrogenase (, ''L-lysine epsilon-dehydrogenase'', ''L-lysine 6-dehydrogenase'', ''LysDH'') is an enzyme with system name ''L-lysine:NAD+ 6-oxidoreductase (deaminating)''. This enzyme catalyses the following chemical reaction
: L-lysine + NAD+ \rightleftharpoons (S)-2,3,4,5-tetrahydropyridine-2-carboxylate + NADH + H+ + NH3 (overall reaction)
: (1a) L-lysine + NAD+ + H2O \rightleftharpoons (S)-2-amino-6-oxohexanoate + NADH + H+ + NH3
: (1b) (S)-2-amino-6-oxohexanoate \rightleftharpoons (S)-2,3,4,5-tetrahydropyridine-2-carboxylate + H2O (spontaneous)
The enzyme is highly specific for L-lysine as substrate, although S-(2-aminoethyl)-L-cysteine can act as a substrate, but more slowly.
== References ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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